Adrafinil‐induced orofacial dyskinesia
Identifieur interne : 000441 ( France/Analysis ); précédent : 000440; suivant : 000442Adrafinil‐induced orofacial dyskinesia
Auteurs : Stéphane Thobois [France] ; Jing Xie [France] ; Helena Mollion [France] ; Isabelle Benatru [France] ; Emmanuel Broussolle [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2004-08.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adrafinil, Aged, Anti-Dyskinesia Agents (therapeutic use), Antihypertensive Agents (adverse effects), Dyskinesia, Dyskinesia, Drug-Induced (drug therapy), Dyskinesia, Drug-Induced (etiology), Humans, Hydroxamic Acids (adverse effects), Hypertension (drug therapy), Male, Motor control, Nervous system diseases, Tetrabenazine (therapeutic use), adrafinil, orofacial dyskinesias, tetrabenazine.
- MESH :
- chemical , adverse effects : Antihypertensive Agents, Hydroxamic Acids.
- chemical , therapeutic use : Anti-Dyskinesia Agents, Tetrabenazine.
- drug therapy : Dyskinesia, Drug-Induced, Hypertension.
- etiology : Dyskinesia, Drug-Induced.
- Aged, Humans, Male.
Abstract
We describe the first case of orofacial abnormal movements induced by adrafinil, a vigilance promoting agent of the same pharmacological class as modafinil. The dyskinesias did not spontaneously recover despite adrafinil withdrawal for a 4‐month period. They were secondly dramatically improved by tetrabenazine, a presynaptic dopaminergic depleting drug which was introduced after the 4‐month adrafinil‐free period. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20154
Affiliations:
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ISTEX:2A9C289DE8CE06EB4B0DC30057317B7DE96F5CB5Le document en format XML
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The dyskinesias did not spontaneously recover despite adrafinil withdrawal for a 4‐month period. 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